Tag Archive: neuroapathy

  1. Rising prevalence of peripheral neuropathy in pre-diabetes patients

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    Kirthi et al. just published a much needed systematic review looking at the rise of peripheral neuropathy in pre-diabetes patients. Not surprisingly, they noted a higher than expected prevalence of neuropathy in this patient population. Interestingly, abnormal small nerve fiber parameters were most notable in this group. This finding aligns with the current consensus that small fiber precedes large fiber degeneration in diabetes. They conclude, “Given the marked rise in pre-diabetes, further consideration of targeting screening in this population is required. Development of risk-stratification tools may facilitate earlier interventions.”

     

  2. Timed Vibration Testing aids in the Diagnosis of Distal Sensory Polyneuropathy

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    A new article written by  Prabhakar et al. has demonstrated the utility of timed vibration testing  in diagnosing distal sensory polyneuropathy (DSP) due to a variety of conditions. They utilized a 128 Hz tuning fork and a handheld stopwatch to time how long patients could feel the vibrations at the hallux, medial malleolus and tibial tuberosity. They noted sensitivity of  85% for the test. Additionally, they were able to conclude that patients with vibration sense lasting >8 seconds at the hallux were free of DSP. Coincidentally, this correlates well with the new 7 second cutoff for early neuropathy on the updated ETF.