CoolVibe-Available for License


  • Billions of injections/vaccinations are performed annually
  • Injections cause significant pain and anxiety for patients
  • Vibration and cold application are known to reduce injection pain


  • CoolVibe combines vibration and cold in a novel configuration to maximize topical analgesia
  • Custom waveforms have been developed to maximally stimulate vibration-sensitive nerve receptors
  • Vibration sources are oriented to result in constructive interference increasing vibration amplitude
  • Vapocoolant skin refrigerant is supplied via integrated, disposable cartridge
  • The vapocoolant stream is aimed at the area of maximal vibration amplitude
  • Stream contacts the skin at the zone of maximal topical analgesia targeting optimal needle placement

Patent Pending: US Patent Application #20220040417

Conceptual Stage Only

Currently Seeking Licensing Partners



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